Wie Aminosäuren bei Darmentzündungen helfen

How Amino Acids Help with Intestinal Inflammation

Dominik Hoffmann

Amino acids – the building blocks of life

Amino acids are the building blocks of life, as virtually every bodily function requires them. There are a total of 21 different amino acids, from which proteins are formed. These proteins are essential for cells, hormones, muscles, and tendons.

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Distinction of Amino Acids

Amino acids are classified into essential, semi-essential, and non-essential amino acids. Essential amino acids cannot be produced by the body and must be obtained through diet. These include: L-Tryptophan, L-Leucine, L-Lysine, L-Valine, L-Phenylalanine, L-Isoleucine, L-Threonine, and L-Methionine.

Semi-essential amino acids are required in higher amounts during specific situations such as pregnancy or intense physical activity. Non-essential amino acids can be synthesized by the body independently.

Amino Acids for the Gut

Empirical medicine and clinical studies show that taking amino acid supplements can support the development and regeneration of the intestinal mucosa. The microbiota (formerly called gut flora) can adhere better to the intestinal lining, thereby supporting the immune system.

Researcher Prof. Dr. Mattner and his team at the University of Erlangen demonstrated that the amino acid L-Arginine influences the composition of the microbiota. A deficiency in L-Arginine leads to an increased accumulation of inflammatory cells in the intestinal wall, which can promote intestinal inflammation.

Conversely, increased intake of L-Arginine positively affects the microbiota and can accelerate the regression of inflammatory processes in the gut.

Gut Bacteria Produce Polyamines

Polyamines are metabolic products of amino acids, act anti-inflammatory, and support the immune system. Higher concentrations of L-Arginine are associated with increased polyamine production in the gut lumen by intestinal bacteria.

These polyamines activate protective genes for intestinal epithelial cells and blood vessels. Patients with chronic inflammatory bowel diseases often have elevated levels of L-Arginine-consuming enzymes. Therefore, L-Arginine is considered a promising therapeutic approach for inflammatory bowel diseases.

Conclusion

Amino acids play a central role for the body and gut health. They support the mucosa and its regeneration. L-Arginine is particularly important, as it positively influences the microbiota and can reduce inflammatory processes in the gut.

HERE you can find our recommended products for intestinal inflammation.

Source: idw-online.de – Research report on L-Arginine and intestinal inflammation

Über den Autor/die Autorin

Dominik Hoffmann

Dominik Hoffmann holds a degree in biology and is the scientific director at HLH BioPharma . With his many years of experience in human biology , microbiome research , and applied health sciences, he combines biological principles with innovative product concepts . In his leadership role, he is responsible for the scientific development and evaluation of dietary supplements and microbiological preparations . His goal: to translate sound science into practical solutions for everyday life – for improved health , well-being , and quality of life .

Portraitaufnahme von Dominik Hoffmann